Variations in peripheral blood cell levels examined in Schistosoma mansoni - infected Holochilus brasiliensis nanus Thomas, 1897, from lower Amazonia, Brazil

Holochilus brasiliensis nanus is a rodent, native to the State of Maranhão, Brazil, which is frequently found when captured to be infected and diseased wich Schistosoma mansoni. It is therefore a useful animal model for experimental studies on schistosomiasis. Studies on the peripheral blood counts...

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Detalles Bibliográficos
Autores: Bastos, Othon de Carvalho, Silva, Sônia M. F., Leal, Grace Mary J. Pires, Bacelar Neto, João M.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1985
País:Brasil
Institución:Universidade de São Paulo (USP)
Repositorio:Revista de Saúde Pública
Idioma:portugués
OAI Identifier:oai:revistas.usp.br:article/23313
Acceso en línea:https://www.revistas.usp.br/rsp/article/view/23313
Access Level:acceso abierto
Palabra clave:Holochilus brasiliensis nanus
Infecção experimental
Schistosoma mansoni
Células sangüíneas
contagem
Roedores silvestres
Experimental infection
Blood cell count
Wild rodents
Descripción
Sumario:Holochilus brasiliensis nanus is a rodent, native to the State of Maranhão, Brazil, which is frequently found when captured to be infected and diseased wich Schistosoma mansoni. It is therefore a useful animal model for experimental studies on schistosomiasis. Studies on the peripheral blood counts in four groups of these rodents are reported. The blood counts of uninfected wild (Group 1) and uninfected laboratory-reared rodents (Group 2) were not found to differ. The laboratory-reared-infected rodents were repeatedly examined over 8 weeks; a progressive rise in the white cell count, and a fall in the red cell count, was noted. Eosinophilia was observed only in the naturally infected wild rodents (Groups 3). These data increased the knowledge regarding the blood counts of these animals when infected with Schistosoma mansoni, information that is important in such a useful natural animal model for schistosomiasis mansoni.